Study and Application of Macroaggregated Albumin labelled with <SUP>131</SUP>I. V : Preparation of <SUP>131</SUP>I-Macroaggregated Albumin
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چکیده
منابع مشابه
Local preparation, standardization and quality control of technetium labelled macroaggregated albumin for lung perfusion studies.
Lung perfusion study is an important investigation in various pulmonary diseases. The radiopharmaceutical commonly used now-a- days is imported macroaggregated human albumin (in kit form), which is labelled with technetium (Tc99m-MAA). Due to its high cost the technique could not be fully exploited. We have tried to locally prepare freeze dried MAA particles. Various parameters like concentrati...
متن کاملEvaluation of LeVeen-shunt patency using Tc-99m labelled macroaggregated albumin.
A LeVeen peritoneo-venous shunt is placed for intractable ascites. Determination of obstruction site in the shunt tube is a difficult problem. We describe a simple nuclear medicine method using 111MBq (3mCi) of Technetium-99m labeled macro-aggregated albumin injected intraperitoneally.
متن کاملExperience with a commercial preparation of 125I-labelled human albumin for study of albumin metabolism.
Evaluation of a commercial preparation of (125)I-labelled albumin for use in the study of albumin metabolism is described. In eight subjects with normal albumin metabolism the proportion of the dose of radioiodide excreted was stable throughout a period of 17 days, indicating that there was no excessive denaturation of the iodinated albumin. Characteristics of albumin metabolism-pool sizes, cat...
متن کاملDirect labeling of macroaggregated albumin with indium-111-chloride using acetate buffer.
UNLABELLED Indium-111-labeled macroaggregated albumin (MAA) would be suitable for combined pulmonary perfusion and ventilation scan using a 99mTc ventilation agent. METHODS MAA suspended in 0.1 M sodium acetate buffer, pH 5.8, was incubated with 111In-chloride for 30 min at room temperature. An in vitro study of the obtained 111In-MAA was performed for labeling efficiency and stability in hum...
متن کاملGenetic immunization with lung-targeting macroaggregated polyethyleneimine-albumin conjugates elicits combined systemic and mucosal immune responses.
Genetic immunization is a novel form of vaccination in which transgenes are delivered into the host to produce the foreign protein within host cells. Although systemic immune responses have been relatively easy to induce by genetic immunization, the induction of regional and mucosal immunity has often been more challenging. To address the problem of eliciting mucosal immunity in the lung, we ut...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1966
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.86.1_20